Shandong Zhanhua Yonghao pharmaceutical & Tech Co.,Ltd

There is no vaccine or cure for HIV infection. However, there are effective treatments that can prevent the transmission of HIV and the progression to AIDS, and help ensure a near-normal life expectancy.

These treatments are known as antiretroviral therapy (ART). They stop the virus from reproducing itself, which leads to a lower viral load. The treatment involves a combination of drugs used together.

HIV-positive people who take ART daily — exactly as prescribed — and achieve (and maintain) an undetectable viral load can’t sexually transmit the virus to an HIV-negative partner.

Thanks to the improvements in treatment, HIV infection is now a manageable chronic disease for many people in countries like Australia.

Tenofovir DF is a prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in adults and children 2 years of age and older who weigh at least 22 lb (10 kg). Tenofovir DF is always used in combination with other HIV medicines.

(DESMP) Diethyl (tosyloxy) methylphosphonate 31618-90-3 Tenofovir intermediates

Basic Info

Product Name: Diethyl P-[[[(4-methylphenyl)sulfonyl]oxy]methyl]phosphonate

Other Name: Phosphonic acid,P-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-,diethyl ester;Phosphonic acid,[[[(4-methylphenyl)sulfonyl]oxy]methyl]-,diethyl ester;Phosphonic acid,(hydroxymethyl)-,diethyl ester,p-toluenesulfonate;Diethyl P-[[[(4-methylphenyl)sulfonyl]oxy]methyl]phosphonate;Tosyloxymethyl diethyl phosphonate;Diethyl (tosyloxy)methylphosphonate;Diethyl [[(p-toluenesulfonyl)oxy]methyl]phosphonate;[[[(4-Tolyl)sulfonyl]oxy]methyl]phosphonic acid diethyl ester;Diethyl p-tosyloxymethylphosphonate;Diethyl [[[(4-tolyl)sulfonyl]oxy]methyl]phosphonate;Diethoxyphosphorylmethyl tosylate;4-Methylbenzenesulfonic acid (diethoxyphosphoryl)methyl ester;(Diethoxyphosphoryl)methyl 4-methylbenzenesulfonate;1422516-21-9;2053249-89-9;2332836-68-5

CAS No.: 31618-90-3

InChIKeys: InChIKey=UOEFFQWLRUBDME-UHFFFAOYSA-N

Molecular Weight: 322.314

Exact Mass: 322.31

EC Number: 608-653-9

DSSTox ID: DTXSID60400648

Categories: Bulk Drug Intermediates

Characteristics

PSA: 97.09000

XLogP3: 1.6

Appearance: Pale yellow oil

Density: 1.3±0.1 g/cm3

Boiling Point: 441.7±28.0 °C at 760 mmHg

Flash Point: 220.9±24.0 °C

Refractive Index: 1.498