Catalogue Number

D445260

Chemical Name

Diethyl p-Toluenesulfonyloxymethylphosphonate

Synonyms

P-[[[(4-Methylphenyl)sulfonyl]oxy]methyl]phosphonic Acid Diethyl Ester; Tosyloxymethyl Diethyl Phosphonate; [[[(4-Tolyl)sulfonyl]oxy]methyl]phosphonic Acid Diethyl Ester; Diethoxyphosphorylmethyl Tosylate; Diethyl (Tosyloxy)methylphosphonate; DESMP; Diethyl [[[(4-Tolyl)sulfonyl]oxy]methyl]phosphonate;

CAS Number

31618-90-3

Molecular Formula

C12H19O6PS

Appearance

Clear Colourless to Pale Yellow Oil

Melting Point

N/A

Molecular Weight

322.31

Storage

Refrigerator, Under Inert Atmosphere

Solubility

Chloroform (Sparingly), Dichloromethane, Ethyl Acetate, Methanol (Sparingly)

Category

Standards; Anti-virals/Anti-retrovirals;

Applications

Diethyl p-Toluenesulfonyloxymethylphosphonate is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor used as an anti-HIV agent.