Shandong Zhanhua Yonghao pharmaceutical & Tech Co.,Ltd

Speaking of "AIDS emergency drug" many people will be relatively unfamiliar, many people do not know the original AIDS also has the so-called "regret medicine". Once substantial "high-risk behavior" occurs, not only accept the fate of waiting to be infected by HIV, the vast majority of cases, can be through post-exposure emergency prophylaxis means to block HIV infection. Today to say in detail about the "AIDS emergency blocking drug" and "high-risk behavior" after how to quickly save themselves? 

What's the deal with the Emergency AIDS Stop? 

Emergency prophylaxis, or PEP (post-exposure prophylaxis), is a high-risk preventive treatment. And "AIDS emergency block" refers to the human body has been exposed to HIV, in a period of time to carry out preventive treatment drugs, can prevent HIV infection of the human body. In general, high-risk behaviors that may lead to HIV transmission and need to be considered for emergency interruption include: sexual contact, including unprotected (no condom/condom breakage) homosexual, heterosexual and multiple sexual contact with an HIV-infected person or suspected HIV-infected person (unidentified); Transmission through blood and blood products, including the importation of blood or blood products that may be infected with HIV, the sharing of needles and intravenous drug use, unsafe interventional medical practices, irregular tattooing, etc.; Vertical mother-to-child transmission, including intrauterine infection of HIV-infected mothers during pregnancy, transmission of HIV to the fetus during delivery and breastfeeding. 

Why does Emergency AIDS Stop HIV transmission? 

In fact, after HIV exposure, the virus is mainly confined to macrophages and dendritic cells in the mucosa of the exposed site (including rectum, genital/tract, and skin lesions), usually within 24 hours after infection. These two kinds of human cells themselves belong to a class of antigen-presenting cells. If the local infection of HIV is not timely and effectively controlled, HIV will be transmitted to lymph nodes with infected macrophages and dendritic cells for "close contact" with T lymphocytes within 24h~48h. Once the T cells in the lymph nodes are infected, the HIV virus has established a "home" in the body, the initial "reservoir" of the virus. The virus can then spread throughout the body through blood and lymphatic circulation, making it impossible for existing treatments to eliminate it. The so-called "AIDS emergency stop" refers to the early stage of exposure, when the HIV virus is mainly confined to the site of exposure, the virus itself is small, and has not formed a stable "virus reservoir". It is possible to block the process of HIV replication in the human body by seizing the precious 72h early treatment with powerful antiviral drugs. HIV emergency block PEP therapy uses a high dose of antiviral drug concentration combined with the body's own strong immune system to identify and clear the few cells infected with HIV. Usually within 72 hours after the occurrence of high-risk behaviors, taking emergency blocking drugs has a high probability of preventing HIV from spreading to the surrounding lymph node tissue and the whole body, thus blocking HIV infection.