Shandong Zhanhua Yonghao
News

Add: GENGJU VILLAGE NORTH ONE KILOMETER,,ZHANHUA DISTRICT,BINZHOU CITY,SHANDONG PROVINCE,CHINA.

+86-543-7596322

Contact Us

News

I believe that one day, mankind will completely overcome AIDS

Date: 2022/10/11

In 1981, the first case of AIDS was diagnosed in the United States. In September 1982, the U.S. Centers for Disease Control and Prevention officially named the disease Acquired Immune Deficiency Syndrome, better known today as AIDS. In the first six years of AIDS, there was no cure.
 
In 1987, the World Health Organization designated December 1 as World AIDS Day. Also that year, Zidovudine (AZT) was certified by the U.S. Food and Drug Administration. It is a milestone in the treatment of AIDS, but the problem with monotherapies is that in addition to being extremely toxic, they can quickly lead to resistance.
 
In 1990, Dr. He and his colleagues figured out how HIV attacks the body's immune system.
 
In 1995, the U.S. Food and Drug Administration approved saquinavir mesylate, the first protease inhibitor to be introduced into the antiretroviral repertoire.
 
In 1996, He introduced "highly active antiretroviral therapy", commonly known as "cocktail therapy". Under Dr He's scheme, this dreaded disease has become a chronic disease that can be managed and treated. It was also the same year that the FDA approved the first viral load test capable of measuring HIV levels in human blood, as well as the first HIV home test kit and the first non-nucleoside drug called nevirapine.
 
In 1998, the Centers for Disease Control and Prevention issued the first national HIV treatment guidelines.
 
In 2002, He transferred his patented technology to the Chinese government for a nominal $1 a year. Free antiviral treatment was also launched in China in 2003. Over the next decade, millions of infected people received free AIDS treatment.
AIDS
In 2004, the AIDS vaccine was jointly developed by the Vaccine Research Center of Jilin University and Changchun Baike Pharmaceutical Co., LTD. It was the first AIDS vaccine approved by the State Food and Drug Administration to enter phase I clinical trials.
 
In 2007, Timothy Ray Brown, the first person in the world to be cured of AIDS.
 
In 2009, researchers from the United States and Thailand jointly announced that a new experimental vaccine can reduce the risk of human infection with HIV by 31.2 percent. This is the world's first AIDS vaccine with a certain immune effect, although its immune effect is still limited, but it has achieved the "immune effect" from nothing to a leap.
 
In 2010, South African AIDS researchers reported at the World AIDS Conference that a medicinal colloid cream could halve a woman's risk of contracting HIV through sex. The medical ointment, called vaginal gel, contains the antiretroviral drug tenofovir.
 
In 2011, Spanish researchers developed a new AIDS vaccine, MV A-B. Entering its second season of testing in humans, the vaccine is expected to weaken the AIDS virus.
 
On November 23, 2016, in new drug development of national science and technology major projects, supported by Chinese scientists independently developed a new generation of anti-aids drugs (HIV fusion inhibitors, YiBoWei tai), by the food and drug supervision administration and national science and technology major projects established drugs oriented "innovative drug approval for examination and approval of the green channel", obtain prior approval, to speed up the review, The drug is expected to be the world's first long-acting injectable anti-AIDS drug, and has already started the verification process for the drug's phase III clinical trial data.
 
On March 5, 2019, Ravindra Gupta, a biologist at the University of Cambridge in the UK, announced that his team had created the second person in human history to be completely cured of HIV/AIDS. The unnamed man has since been given a code name that will go down in history - the London Patient.
 
On September 12, 2019, the New England journal of medicine published online hongkui deng professor of school of life science in our country, the people's liberation army general hospital medical center is professor Chen tiger hu, 5 an hospital affiliated to the capital university of medical sciences, professor waley team cooperation, such as editing techniques with CRISPR genes deactivation CCR5 genes in human hematopoietic stem cells, The edited stem cells were transplanted into an AIDS patient with acute lymphoblastic leukemia. Inactivated CCR5 stem cells are reinfused to help AIDS patients develop an immune system strong enough to fight off the virus.
 
On February 15, 2022, US researchers reported the world's first female HIV/AIDS survivor at an academic conference. She is the third person to be cured of HIV infection. After treatment and discontinuation of antiviral drugs, the patient remained HIV-free for more than 14 months, suggesting that her infection was in complete remission.
......
This Dec. 1, will be the 35th World AIDS Day. From 1981 to today, AIDS has been with us for 41 years. I believe that one day, mankind will completely overcome AIDS.
 
Extended reading:
 
Product Description of Diethyl p-Toluenesulfonyloxymethylphosphonate
Catalogue Number: D445260
Chemical Name: Diethyl p-Toluenesulfonyloxymethylphosphonate
Synonyms: P-[[[(4-Methylphenyl)sulfonyl]oxy]methyl]phosphonic Acid Diethyl Ester; Tosyloxymethyl Diethyl Phosphonate; [[[(4-Tolyl)sulfonyl]oxy]methyl]phosphonic Acid Diethyl Ester; Diethoxyphosphorylmethyl Tosylate; Diethyl (Tosyloxy)methylphosphonate; DESMP; Diethyl [[[(4-Tolyl)sulfonyl]oxy]methyl]phosphonate;
CAS Number: 31618-90-3
Molecular Formula: C12H19O6PS
Appearance: Clear Colourless to Pale Yellow Oil
Melting Point: N/A
Molecular Weight: 322.31
Storage: Refrigerator, Under Inert Atmosphere
Solubility: Chloroform (Sparingly), Dichloromethane, Ethyl Acetate, Methanol (Sparingly)
Category Standards: Anti-virals/Anti-retrovirals;
Applications: Diethyl p-Toluenesulfonyloxymethylphosphonate is an antiviral agent and a Tenofovir (T018500) intermediate. Tenofovir is an acyclic phosphonate nucleotide analogue and reverse transcriptase inhibitor used as an anti-HIV agent.

Last : The clinic... 】 【[ Back ]Next : Is Tenofov...


 

Shandong Zhanhua Yonghao pharmaceutical & Tech Co.,Ltd
      Add: GENGJU VILLAGE NORTH ONE KILOMETER,,ZHANHUA DISTRICT,BINZHOU CITY,SHANDONG PROVINCE,CHINA.
      Tel: +86-543-7596322    Fax: +86-543-7596300
      Sales add: C ZONE,7TH F.L.,NEW TAIZHOU BLDG.,TAIZHOU,ZHEJIANG PROVINCE,CHINA
      Sale Tel: +86-576-0576-88685096/88810310/88603655
      Fax: +86-576-88685099
      E-mail: sales@yfchem.cn

Copyright(C)2017,Shandong Zhanhua Yonghao pharmaceutical & Tech Co.,Ltd All Rights Reserved. Supported by ChemNet ChinaChemNet Toocle Copyright Notice